AP®︎ Biology: Topic 6.6 Practice Test
Prepare for your quiz, test, or the AP exam with focused practice questions on Topic 6.6 of AP Biology – Gene Expression and Cell Specialization.
Questions List
Topic 6.6
Question 1 Easy
This question tests the following: IST-2.C
What molecule binds to promoters to initiate transcription?
What You’re Being Tested On:
Explore the learning objectives taken directly from the College Board’s AP® Biology Curriculum. Ensure you’re prepared for the exact topics covered on the AP® exam, in-class tests, and quizzes, and gain confidence in your mastery of the material.

Topic 6.6: Gene Expression and Cell Specialization
Learning Objective: 6.6.A
Explain how the binding of transcription factors to promoter regions affects gene expression and the phenotype of the organism.
Essential Knowledge: 6.6.A.1
RNA polymerase and transcription factors bind to promoter or enhancer DNA sequences to initiate transcription. These sequences can be upstream or downstream of the transcription start site.
Essential Knowledge: 6.6.A.2
Negative regulatory molecules inhibit gene expression by binding to DNA and blocking transcription.
Learning Objective: 6.6.B
Explain the connection between the regulation of gene expression and phenotypic differences in cells and organisms.
Essential Knowledge: 6.6.B.1
Gene regulation results in differential gene expression and influences cell products and functions.
Essential Knowledge: 6.6.B.2
Certain small RNA molecules have roles in regulating gene expression.