AP®︎ Biology: Topic 4.6 Flashcards

Master key terms and definitions for Topic 4.6 of AP Biology – Regulation of Cell Cycle to help you prep for quizzes and the AP exam.

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Term

Cell Cycle Checkpoints

Definition

Internal control points that stop or allow progression only when key conditions are met.

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Cell Cycle Checkpoints
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Internal control points that stop or allow progression only when key conditions are met.

4.6.A4.6.A.1
G1, G2, and M Checkpoints
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G1 checks size, nutrients, signals, and DNA; G2 checks replication and damage; M checks spindle attachment.

4.6.A4.6.A.1
G0 Phase
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A resting, nondividing state entered when a cell does not continue past G1.

4.6.A4.6.A.1
Cyclins and Cyclin-Dependent Kinases (CDKs)
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Regulatory proteins where cyclins activate CDKs to drive cell cycle transitions.

4.6.A4.6.A.2
Cyclin and CDK Activity Pattern
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Cyclin levels fluctuate, while CDK levels stay relatively constant and work only when activated.

4.6.A4.6.A.2
Cancer
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Uncontrolled cell division caused by failed regulation and checkpoint bypass.

4.6.B4.6.B.1
Apoptosis
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Programmed cell death that eliminates cells damaged beyond repair.

4.6.B4.6.B.1