AP®︎ Biology: Topic 3.5 Flashcards

Master key terms and definitions for Topic 3.5 of AP Biology – Cellular Respiration to help you prep for quizzes and the AP exam.


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Term

Cellular Respiration

Definition

Process that breaks down organic molecules to make ATP through enzyme-catalyzed energy transfer.

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Cellular Respiration
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Process that breaks down organic molecules to make ATP through enzyme-catalyzed energy transfer.

3.5.A3.5.A.1
Aerobic Respiration vs. Fermentation
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Aerobic uses oxygen and yields much more ATP; fermentation regenerates NAD+ without oxygen and yields 2 ATP.

3.5.B3.5.B.6
Mitochondrion
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Double-membraned organelle where pyruvate oxidation, the Krebs cycle, and oxidative phosphorylation occur in eukaryotes.

3.5.A3.5.A.2
Inner Mitochondrial Membrane / Cristae
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Highly folded membrane containing the ETC and ATP synthase; folds increase surface area for ATP production.

3.5.A3.5.A.3
Mitochondrial Matrix
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Innermost compartment of the mitochondrion where pyruvate oxidation and the Krebs cycle occur.

3.5.B3.5.B.3
Intermembrane Space
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Compartment between mitochondrial membranes where protons accumulate during electron transport.

3.5.B3.5.B.5
Glycolysis
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Cytoplasmic pathway that splits glucose into two pyruvate, producing net 2 ATP and 2 NADH.

3.5.B3.5.B.1
Pyruvate Oxidation
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Conversion of pyruvate to acetyl CoA in mitochondria, releasing CO2 and producing NADH.

3.5.B3.5.B.2
Krebs Cycle / Citric Acid Cycle
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Matrix pathway that oxidizes acetyl CoA, releasing CO2 and producing ATP, NADH, and FADH2.

3.5.B3.5.B.3
NAD+ / NADH
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Electron carrier that accepts high-energy electrons and hydrogen, then delivers them to the ETC.

3.5.B3.5.B.4
FAD / FADH2
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Electron carrier reduced during the Krebs cycle that transfers electrons to the ETC.

3.5.B3.5.B.4
Electron Transport Chain
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Series of membrane proteins that pass electrons through redox reactions and pump protons across a membrane.

3.5.A3.5.A.3
Proton Gradient / Electrochemical Gradient
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Difference in H+ concentration and charge across a membrane created by electron transport.

3.5.B3.5.B.5
Chemiosmosis
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Diffusion of protons through ATP synthase down their gradient, driving ATP formation.

3.5.A3.5.A.3
ATP Synthase
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Membrane enzyme that uses proton flow to phosphorylate ADP into ATP.

3.5.A3.5.A.3
Oxidative Phosphorylation
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ATP production powered by chemiosmosis and linked to electron transport in aerobic respiration.

3.5.A3.5.A.3
Matrix pH vs. Intermembrane Space pH
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The matrix has lower H+ concentration and higher pH than the intermembrane space.

3.5.B3.5.B.5
Substrate-Level Phosphorylation
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Direct enzymatic transfer of a phosphate group to ADP to form ATP.

3.5.B
Lactic Acid Fermentation
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Anaerobic pathway that reduces pyruvate to lactate and regenerates NAD+ for glycolysis.

3.5.B3.5.B.6
Alcoholic Fermentation
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Anaerobic pathway that converts pyruvate to ethanol and CO2 while regenerating NAD+.

3.5.B3.5.B.6
Decoupling of Electron Transport and Oxidative Phosphorylation
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When proton gradient energy is released as heat instead of being used to make ATP.

3.5.A3.5.A.3
Prokaryotic Cellular Respiration
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In prokaryotes, electron transport and proton pumping occur across the plasma membrane.

3.5.A3.5.A.3
Terminal Electron Acceptor
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Final molecule that receives electrons; in aerobic respiration, oxygen forms water.

3.5.A3.5.A.3
Acetyl CoA
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Two-carbon molecule formed from pyruvate that enters the Krebs cycle.

3.5.B3.5.B.2